PDS5B antibody (Middle Region)

Catalog No. ABIN2787631

The Rabbit Polyclonal anti-PDS5B antibody (ABIN2787631) specifically detects PDS5B in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for PDS5B antibody (Middle Region) (ABIN2787631)

Target: PDS5B (PDS5, Regulator of Cohesion Maintenance, Homolog B (PDS5B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDS5B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDS5B Antibody

Binding Specificity: Middle Region

Sequence: DEQQWPEEKR LKEDILENED EQNSPPKKGK RGRPPKPLGG GTPKEEPTMK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against PDS5B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDS5B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1447 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDS5B

Target: PDS5B (PDS5, Regulator of Cohesion Maintenance, Homolog B (PDS5B))

Alternative Name: PDS5B

Background: PDS5B plays a role in androgen-induced proliferative arrest in prostate cells. It is required for maintenance of sister chromatid cohesion during mitosis. Defects in PDS5B may be the cause of some cancers including esophageal cancer.
Alias Symbols: APRIN, AS3, CG008, FLJ23236, KIAA0979, RP1-267P19.1
Protein Interaction Partner: UBC, EED, RNF2, CDCA5, LAMP2, APP, NSMCE2, SIRT7, RAD21, STAG2, STAG1, SMC3, SMC1A, SUMO1, WAPAL, WFDC5, PDS5A, tat,
Protein Size: 1447

Molecular Weight: 159 kDa

Gene ID: 23047

NCBI Accession: NM_015032, NP_055847

UniProt: Q9NTI5