IGF2BP1 antibody (N-Term)

Catalog No. ABIN2787659

This Rabbit Polyclonal antibody specifically detects IGF2BP1 in WB and IHC. It exhibits reactivity toward Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Guinea Pig, Sheep and Zebrafish (Danio rerio).

Quick Overview for IGF2BP1 antibody (N-Term) (ABIN2787659)

Target: IGF2BP1 (Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1))

Reactivity: Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Guinea Pig, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2BP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IGF2BP1 Antibody

Binding Specificity: N-Term

Sequence: AFVDCPDEHW AMKAIETFSG KVELQGKRLE IEHSVPKKQR SRKIQIRNIP P

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against IGF2BP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IGF2BP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 577 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IGF2BP1

Target: IGF2BP1 (Insulin-Like Growth Factor 2 mRNA Binding Protein 1 (IGF2BP1))

Alternative Name: IGF2BP1

Background: IGF2BP1 is a member of the IGF-II mRNA-binding protein (IMP) family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1
Protein Interaction Partner: HAUS2, TUBGCP2, TUBGCP3, TP53, AURKA, CDKN1A, TUBGCP4, CEP250, IVNS1ABP, STAU1, UBC, WWOX, PARK2, FBXO6, BAG3, PAN2, VCAM1, ITGA4, IFIT1, GRB2, FN1, CBX6, CBX8, SYNCRIP, BIRC2, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5, NEDD8, gag, BTRC, ARRB2, Y
Protein Size: 577

Molecular Weight: 63 kDa

Gene ID: 10642

NCBI Accession: NM_006546, NP_006537

UniProt: Q9NZI8