FKBP2 antibody (N-Term)

Catalog No. ABIN2787694

The Rabbit Polyclonal anti-FKBP2 antibody has been validated for WB. It is suitable to detect FKBP2 in samples from Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for FKBP2 antibody (N-Term) (ABIN2787694)

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FKBP2 Antibody

Binding Specificity: N-Term

Sequence: RLSWFRVLTV LSICLSAVAT ATGAEGKRKL QIGVKKRVDH CPIKSRKGDV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against FKBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 142 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FKBP2

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Alternative Name: FKBP2

Background: FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.
Alias Symbols: FKBP-13, PPIase
Protein Interaction Partner: UBQLN1, RAB3C, VAMP2, RAB6A, UBC, BARD1, UBQLN4, PTGES3, RAP2A, MAPK3, ARFGEF1, EPB41L2, BAG6, EPB41, C1QC, ARFGEF2, CDKN2A,
Protein Size: 142

Molecular Weight: 16 kDa

Gene ID: 2286

NCBI Accession: NM_004470, NP_004461

UniProt: P26885