FRS3 antibody (C-Term)

Catalog No. ABIN2787696

The Rabbit Polyclonal anti-FRS3 antibody (ABIN2787696) specifically detects FRS3 in WB. The antibody is reactive with Human, Rat, Mouse, Dog, Horse, Rabbit, Cow, Guinea Pig and Zebrafish (Danio rerio) samples.

Quick Overview for FRS3 antibody (C-Term) (ABIN2787696)

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Reactivity: Human, Rat, Mouse, Dog, Horse, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRS3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FRS3 Antibody

Binding Specificity: C-Term

Sequence: APGPTPHPVR SSDSYAVIDL KKTAAMSDLQ RALPRDDGAV RKTRHNSTDL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against Frs3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Frs3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 492 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FRS3

Target: FRS3 (Fibroblast Growth Factor Receptor Substrate 3 (FRS3))

Alternative Name: Frs3

Background: Frs3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. It is involved in the activation of MAP kinases. Frs3 Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Alias Symbols: 4930417B13Rik, AI449674, Frs2beta, MGC25496, Snt2
Protein Interaction Partner: Bmpr2,
Protein Size: 492

Molecular Weight: 54 kDa

Gene ID: 107971

NCBI Accession: NM_144939, NP_659188

UniProt: Q91WJ0