TXNDC5 antibody (N-Term)

Catalog No. ABIN2787735

The Rabbit Polyclonal anti-TXNDC5 antibody is suitable to detect TXNDC5 in samples from Human. It has been validated for WB.

Quick Overview for TXNDC5 antibody (N-Term) (ABIN2787735)

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TXNDC5 Antibody

Binding Specificity: N-Term

Sequence: ARAQEAAAAA ADGPPAADGE DGQDPHSKHL YTADMFTHGI QSAAHFVMFF

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TXNDC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TXNDC5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 432 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TXNDC5

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Alternative Name: TXNDC5

Background: TXNDC5 is a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis.This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. This gene can be co-transcribed with the upstream gene MU.
Alias Symbols: ERP46, EndoPDI, MGC3178, UNQ364, HCC-2, STRF8, PDIA15, ENDOPDI
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-9, KRTAP10-7, TRIM42, MGAT5B, ALS2CR12, KRT40, LHX4, KRTAP4-2, EFEMP1, KRTAP4-12, GMPPB, SPRY2, KRT38, BLZF1, TRIP6, TRIM23, UBC, SUMO1, NEDD8, MDM2, EED, YWHAQ, BZW1, YWHAG, UBE2V1, TGM2, PGD, LDHB, GNAI
Protein Size: 432

Molecular Weight: 48 kDa

Gene ID: 81567

NCBI Accession: NM_030810, NP_110437

UniProt: Q8NBS9

Pathways: Cell RedoxHomeostasis