EFHD2 antibody (N-Term)

Catalog No. ABIN2787767

This Rabbit Polyclonal antibody specifically detects EFHD2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Pig and Saccharomyces cerevisiae.

Quick Overview for EFHD2 antibody (N-Term) (ABIN2787767)

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFHD2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EFHD2 Antibody

Binding Specificity: N-Term

Sequence: MGTPGEGLGR CSHALIRGVP ESLASGEGAG AGLPALDLAK AQREHGVLGG

Predicted Reactivity: Cow: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 93%, Yeast: 83%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against EFHD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EFHD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 240 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EFHD2

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Alternative Name: EFHD2

Background: EFHD2 may regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. It plays a role as negative regulator of the canonical NF-kappa-B-activating branch. EFHD2 controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Alias Symbols: MGC4342, RP3-467K16.3, SWS1
Protein Interaction Partner: UBC, COASY, CHMP4A, GLRX3, GMPS, TSTA3, RCN1, PTPN11, IDH1, ENO2, DCK, FBXO6, PAN2, APP, LRRK2, ELAVL1,
Protein Size: 240

Molecular Weight: 26 kDa

Gene ID: 79180

NCBI Accession: NM_024329, NP_077305

UniProt: Q96C19