UBAC1 antibody (N-Term)

Catalog No. ABIN2787790

This Rabbit Polyclonal antibody specifically detects UBAC1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Cow and Zebrafish (Danio rerio).

Quick Overview for UBAC1 antibody (N-Term) (ABIN2787790)

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBAC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBAC1 Antibody

Binding Specificity: N-Term

Sequence: DGAEWLEEAT EDTSVEKLKE RCLKHCAHGS LEDPKSITHH KLIHAASERV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against UBAC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBAC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBAC1

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Alternative Name: UBAC1

Background: UBAC1 is a non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. It is required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
Alias Symbols: GBDR1, RP11-432J22.3, UBADC1
Protein Interaction Partner: TRIM39, TRIM2, DAZAP2, UBC, HTT, UNC119B, VPS25, UTP6, RPS6KA6, TWF2, USP7, TCEA1, APP, AIRE, CSNK2A1, RAD23A, NEDD4L, RNF123, CDKN1B, PSMD6, PSMD7, PSMD4, RNF11, CPSF6, LAPTM5, IQGAP2, MED7, MYH2, EIF4EBP1,
Protein Size: 405

Molecular Weight: 44 kDa

Gene ID: 10422

NCBI Accession: NM_016172, NP_057256

UniProt: Q9BSL1