UBAC1 antibody (N-Term)

Catalog No. ABIN2787790

Product Details anti-UBAC1 Antibody

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBAC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DGAEWLEEAT EDTSVEKLKE RCLKHCAHGS LEDPKSITHH KLIHAASERV

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against UBAC1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBAC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBAC1

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Alternative Name: UBAC1 (UBAC1 Products)

Background: UBAC1 is a non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. It is required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
Alias Symbols: GBDR1, RP11-432J22.3, UBADC1
Protein Interaction Partner: TRIM39, TRIM2, DAZAP2, UBC, HTT, UNC119B, VPS25, UTP6, RPS6KA6, TWF2, USP7, TCEA1, APP, AIRE, CSNK2A1, RAD23A, NEDD4L, RNF123, CDKN1B, PSMD6, PSMD7, PSMD4, RNF11, CPSF6, LAPTM5, IQGAP2, MED7, MYH2, EIF4EBP1,
Protein Size: 405

Molecular Weight: 44 kDa

Gene ID: 10422

NCBI Accession: NM_016172, NP_057256

UniProt: Q9BSL1