UBAC1 antibody (AA 60-140)

Catalog No. ABIN7215018

The Rabbit Polyclonal anti-UBAC1 antibody is suitable to detect UBAC1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for UBAC1 antibody (AA 60-140) (ABIN7215018)

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBAC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-UBAC1 Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-GBDR1 Polyclonal Antibody

Specificity: GBDR1 Polyclonal Antibody detects endogenous levels of GBDR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GBDR1 at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBAC1

Target: UBAC1 (UBA Domain Containing 1 (UBAC1))

Alternative Name: GBDR1

Background: UBAC1, GBDR1, KPC2, UBADC1, Ubiquitin-associated domain-containing protein 1, UBA domain-containing protein 1, E3 ubiquitin-protein ligase subunit KPC2, Glialblastoma cell differentiation-related protein 1, Kip1 ubiquitination-promoting comUbiquitin-associated domain-containing protein 1 is a non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle. Diseases associated with UBAC1 include acute cystitis and bladder disease. Among its related pathways are Immune System and Antigen processing- Ubiquitination and Proteasome degradation.

Molecular Weight: 45kD

Gene ID: 10422

UniProt: Q9BSL1