RASGRP2 antibody (N-Term)

Catalog No. ABIN2787843

This anti-RASGRP2 antibody is a Rabbit Polyclonal antibody detecting RASGRP2 in WB. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Cow and Rabbit.

Quick Overview for RASGRP2 antibody (N-Term) (ABIN2787843)

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGRP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RASGRP2 Antibody

Binding Specificity: N-Term

Sequence: LVRMFLMMHP WYIPSSQLAA KLLHIYQQSR KDNSNSLQVK TCHLVRYWIS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RASGRP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RASGRP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 609 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RASGRP2

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Alternative Name: RASGRP2

Background: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can act
Alias Symbols: CALDAG-GEFI, CDC25L
Protein Interaction Partner: UBC, APP, PTCHD2, FAM118B, KRAS, RAP1A, NRAS,
Protein Size: 609

Molecular Weight: 69 kDa

Gene ID: 10235

NCBI Accession: NM_153819, NP_722541

UniProt: Q7LDG7

Pathways: TCR Signaling