Nucleostemin antibody (N-Term)

Catalog No. ABIN2787845

The Rabbit Polyclonal anti-Nucleostemin antibody has been validated for WB. It is suitable to detect Nucleostemin in samples from Human, Mouse, Rat, Horse, Dog, Rabbit, Guinea Pig and Cow.

Quick Overview for Nucleostemin antibody (N-Term) (ABIN2787845)

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Reactivity: Human, Mouse, Rat, Horse, Dog, Rabbit, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nucleostemin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nucleostemin Antibody

Binding Specificity: N-Term

Sequence: MTCHKRYKIQ KKVREHHRKL RKEAKKRGHK KPRKDPGVPN SAPFKEALLR

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GNL3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GNL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 537 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Nucleostemin

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Alternative Name: GNL3

Background: GNL3 may be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis.
Alias Symbols: C77032, E2IG3, MGC800, NS, NNP47
Protein Interaction Partner: SUMO3, UBC, TRIP12, MDM2, CDKN2A, EED, RNF2, SRPK3, TARDBP, EIF2AK2, MPG, WHSC1, STAT3, ESR1, RPL5, RPL4, NOP2, RPL6, RPLP0P6, FTSJ3, NIFK, BCCIP, NOP58, RRP7A, NHP2L1, EIF6, FBL, BOP1, RRS1, DIDO1, EBNA1BP2, RNPS1, NOP56, EIF4A3, RPL23, RPS24, RPS15A, RP
Protein Size: 537

Molecular Weight: 60 kDa

Gene ID: 26354

NCBI Accession: NM_206825, NP_996561