ULK3 antibody (Middle Region)

Catalog No. ABIN2787898

The Rabbit Polyclonal anti-ULK3 antibody has been validated for WB. It is suitable to detect ULK3 in samples from Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Rabbit and Horse.

Quick Overview for ULK3 antibody (Middle Region) (ABIN2787898)

Target: ULK3 (Unc-51-Like Kinase 3 (ULK3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ULK3 Antibody

Binding Specificity: Middle Region

Sequence: LGRATALVVQ AVKKDQEGDS AAALSLYCKA LDFFVPALHY EVDAQRKEAI

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ULK3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ULK3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 472 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ULK3

Target: ULK3 (Unc-51-Like Kinase 3 (ULK3))

Alternative Name: ULK3

Background: ULK3 is the serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. ULK3 may exert this function by promoting GLI1 nuclear localization. ULK3 phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.
Alias Symbols: DKFZp434C131, FLJ90566
Protein Interaction Partner: VCP, WDR82, UBC,
Protein Size: 472

Molecular Weight: 53 kDa

Gene ID: 25989

NCBI Accession: NM_001099436, NP_001092906

UniProt: Q6PHR2