ULK3 antibody (Internal Region)
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- Target See all ULK3 Antibodies
- ULK3 (Unc-51-Like Kinase 3 (ULK3))
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Binding Specificity
- Internal Region
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ULK3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- ULK3 Antibody detects endogenous levels of total ULK3.
- Predicted Reactivity
- Horse,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human ULK3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product ULK3 Primary Antibody
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anti-Unc-51-Like Kinase 3 (ULK3) (AA 14-43), (N-Term) antibody
ULK3 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB12633 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (HRP)ULK3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal HRP
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (FITC)ULK3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal FITC
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (PE)ULK3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal PE
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (PerCP)ULK3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal PerCP
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (Atto 594)ULK3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal Atto 594
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (Atto 488)ULK3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal Atto 488
anti-Unc-51-Like Kinase 3 (ULK3) (AA 166-177) antibody (Atto 390)ULK3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal Atto 390
anti-Unc-51-Like Kinase 3 (ULK3) (AA 435-468), (C-Term) antibodyULK3 Reactivity: Human, Mouse, Rat WB Host: Mouse Monoclonal 1404CT148-89-25 unconjugated
anti-Unc-51-Like Kinase 3 (ULK3) antibodyULK3 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
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- Application Notes
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- ULK3 (Unc-51-Like Kinase 3 (ULK3))
- Alternative Name
- ULK3 (ULK3 Products)
- Synonyms
- zgc:162196 antibody, 1200015E14Rik antibody, unc-51 like kinase 3 antibody, unc-51 like kinase 3 L homeolog antibody, unc-51-like kinase 3 antibody, ULK3 antibody, ulk3 antibody, Ulk3 antibody, ulk3.L antibody
- Background
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Description: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
Gene: ULK3
- Molecular Weight
- 24 kDa
- Gene ID
- 25989
- UniProt
- Q6PHR2
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