CD28 antibody (C-Term)

Catalog No. ABIN2787933

This anti-CD28 antibody is a Rabbit Polyclonal antibody detecting CD28 in WB. Suitable for Human, Mouse, Rat, Cow, Pig, Sheep, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for CD28 antibody (C-Term) (ABIN2787933)

Target: CD28

Reactivity: Human, Mouse, Rat, Cow, Pig, Sheep, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD28 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD28 Antibody

Binding Specificity: C-Term

Sequence: TVAFIIFWVR SKRSRLLHSD YMNMTPRRPG PTRKHYQPYA PPRDFAAYRS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CD28. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CD28

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 220 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD28

Target: CD28

Alternative Name: CD28

Background: CD28 is involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
Alias Symbols: MGC138290, Tp44
Protein Interaction Partner: VAV1, DOK1, LRRC23, CD80, UBC, PIK3R2, PIK3R1, PIK3CA, DUSP14, GRAP2, NSF, PIK3CG, CD86, ITK, CD4, CD247, PLCG1, IL12A, LCK, PTPRC, GRB2,
Protein Size: 220

Molecular Weight: 25 kDa

Gene ID: 940

NCBI Accession: NM_006139, NP_006130

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response