RNF128 antibody (C-Term)

Catalog No. ABIN617092

This Rabbit Polyclonal antibody specifically detects RNF128 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit and Pig.

Quick Overview for RNF128 antibody (C-Term) (ABIN617092)

Target: RNF128 (Ring Finger Protein 128 (RNF128))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF128 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNF128 Antibody

Binding Specificity: C-Term

Sequence: PMCKCDILKA LGIEVDVEDG SVSLQVPVSN EISNSASSHE EDNRSETASS

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 402 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNF128

Target: RNF128 (Ring Finger Protein 128 (RNF128))

Alternative Name: RNF128

Background: RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.
Alias Symbols: FLJ23516, GRAIL
Protein Interaction Partner: CEP76, APPBP2, TP53, UBE2H, UBE2E1, UBE2D1, Arhgdia, Arhgdib, RNF128, UBE2T, UBE2I, UBE2N, CD40LG, OTUB1, USP8,
Protein Size: 402

Molecular Weight: 44 kDa

Gene ID: 79589

NCBI Accession: NM_024539, NP_078815