LAX1 antibody (C-Term)

Catalog No. ABIN2787949

The Rabbit Polyclonal anti-LAX1 antibody has been validated for WB. It is suitable to detect LAX1 in samples from Human, Mouse, Rat, Dog and Pig.

Quick Overview for LAX1 antibody (C-Term) (ABIN2787949)

Target: LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LAX1 Antibody

Binding Specificity: C-Term

Sequence: ADFQPFTQSE DSQMKHREEM SNEDSSDYEN VLTAKLGGRD SEQGPGTQLL

Predicted Reactivity: Dog: 86%, Human: 100%, Mouse: 79%, Pig: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against LAX1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LAX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 382 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LAX1

Target: LAX1 (Lymphocyte Transmembrane Adaptor 1 (LAX1))

Alternative Name: LAX1

Background: LAX1 is a single-pass type III membrane protein. It negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Alias Symbols: FLJ20340, LAX
Protein Interaction Partner: STAMBPL1, GRB7, NDN, UBC, GRAP2, SYK, ZAP70, LCK, GRB2,
Protein Size: 382

Molecular Weight: 42 kDa

Gene ID: 54900

NCBI Accession: NM_001136190, NP_001129662

UniProt: B7Z744

Pathways: Production of Molecular Mediator of Immune Response