alpha 2 Antiplasmin antibody (N-Term)

Catalog No. ABIN2787972

This Rabbit Polyclonal antibody specifically detects alpha 2 Antiplasmin in WB. It exhibits reactivity toward Human, Cow and Horse.

Quick Overview for alpha 2 Antiplasmin antibody (N-Term) (ABIN2787972)

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Reactivity: Human, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha 2 Antiplasmin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-alpha 2 Antiplasmin Antibody

Binding Specificity: N-Term

Sequence: CSRDPTPEQT HRLARAMMAF TADLFSLVAQ TSTCPNLILS PLSVALALSH

Predicted Reactivity: Cow: 91%, Horse: 100%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SERPINF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SERPINF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 491 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for alpha 2 Antiplasmin

Target: alpha 2 Antiplasmin (SERPINF2) (Alpha2 Antiplasmin (SERPINF2))

Alternative Name: SERPINF2

Background: This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: A2AP, AAP, ALPHA-2-PI, API, PLI
Protein Interaction Partner: FN1, BCAP31, SSR1, UBC, CANX, SERPINB12, F11, KLK13, KLK6, PRSS1, SERPINF2, PLAU, TGM2, PLG, KLK2, FGA, F13A1, CFD, ELANE, DEFA1, CTRB1,
Protein Size: 491

Molecular Weight: 54 kDa

Gene ID: 5345

NCBI Accession: NM_000934, NP_000925

UniProt: P08697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones