USP10 antibody (C-Term)
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- Target See all USP10 Antibodies
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This USP10 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RDIRPGAAFE PTYIYRLLTV IKSSLSEKGR QEDAEEYLGF ILNGLHEEML
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Usp10. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product USP10 Primary Antibody
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anti-Ubiquitin Specific Peptidase 10 (USP10) antibody
USP10 Reactivity: Human, Mouse, Rat, Monkey, Dog WB, IF, IHC, IHC (p), FACS Host: Mouse Monoclonal 2E1 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) antibodyUSP10 Reactivity: Human WB, IHC, IHC (p), FACS Host: Mouse Monoclonal 1A10 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) antibodyUSP10 Reactivity: Human, Monkey WB, IHC, IHC (p), FACS Host: Mouse Monoclonal 1H9 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 1-798) antibodyUSP10 Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 699-797) antibodyUSP10 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3B8 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 1-798) antibodyUSP10 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) antibodyUSP10 Reactivity: Human WB, IF, IP Host: Rabbit Monoclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (N-Term) antibodyUSP10 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (AA 500-529) antibodyUSP10 Reactivity: Human WB Host: Rabbit Polyclonal RB36758 unconjugated
anti-Ubiquitin Specific Peptidase 10 (USP10) (C-Term) antibodyUSP10 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 794 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
- Alternative Name
- Usp10 (USP10 Products)
- Background
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Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.
Alias Symbols: MGC124997
Protein Size: 794 - Molecular Weight
- 87 kDa
- Gene ID
- 307905
- NCBI Accession
- NM_001034146, NP_001029318
- UniProt
- Q3KR59
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