USP10 antibody (Middle Region)

Catalog No. ABIN2788017

This Rabbit Polyclonal antibody specifically detects USP10 in WB. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for USP10 antibody (Middle Region) (ABIN2788017)

Target: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP10 Antibody

Binding Specificity: Middle Region

Sequence: GVELHTTESI DLDPTKPESA SPPADGTGSA SGTLPVSQPK SWASLFHDSK

Predicted Reactivity: Cow: 77%, Human: 100%, Mouse: 77%, Rat: 77%

Characteristics: This is a rabbit polyclonal antibody against USP10. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 798 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP10

Target: USP10 (Ubiquitin Specific Peptidase 10 (USP10))

Alternative Name: USP10

Background: Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene.
Alias Symbols: KIAA0190, MGC2621, UBPO
Protein Interaction Partner: G3BP2, G3BP1, USP10, TP53, SUMO2, TBX21, UBC, ZC3H12A, IKBKG, PCNA, PTEN, HECW2, PPP6R3, TARDBP, ANKRD28, PPP6R1, PABPC1, VCP, ZC3H18, TRPM8, TSKS, UBE2S, ZNF281, WAPAL, USP15, CFTR, AR, MDM2, ULK1, GAR1, CELF1, EIF4G3, EIF4G1, SNX3, SCNN1A,
Protein Size: 798

Molecular Weight: 87 kDa

Gene ID: 9100

NCBI Accession: NM_005153, NP_005144

UniProt: Q14694