ZRANB1 antibody (C-Term)

Catalog No. ABIN2788030

The Rabbit Polyclonal anti-ZRANB1 antibody has been validated for WB. It is suitable to detect ZRANB1 in samples from Human, Mouse, Cow, Dog, Horse, Rabbit, Rat, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for ZRANB1 antibody (C-Term) (ABIN2788030)

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Reactivity: Human, Mouse, Cow, Dog, Horse, Rabbit, Rat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZRANB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZRANB1 Antibody

Binding Specificity: C-Term

Sequence: GAGANLNTDD DVTITFLPLV DSERKLLHVH FLSAQELGNE EQQEKLLREW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ZRANB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZRANB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 708 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZRANB1

Target: ZRANB1 (Zinc Finger, RAN-Binding Domain Containing 1 (ZRANB1))

Alternative Name: ZRANB1

Background: ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains.ZRANB1 acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. ZRANB1 may also modulate TNF-alpha signaling.
Alias Symbols: DKFZp762P2216, TRABID
Protein Interaction Partner: Btrc, UBC, CORO7, STRIP1, CTTNBP2, CTTNBP2NL, STRN3, STRN4, HECTD1, SLMAP, STRN, UBE2S, TRAF6, Apc, PGAM5, STRIP2, CACYBP, FGFR1OP2, MOB4, BICD2, FBXW11, KEAP1, GCC2, MAP4K4, HERC2, ALDH18A1, PPP2R1B,
Protein Size: 708

Molecular Weight: 81 kDa

Gene ID: 54764

NCBI Accession: NM_017580, NP_060050

UniProt: Q9UGI0