UBL4A antibody (Middle Region)

Catalog No. ABIN2788049

Product Details anti-UBL4A Antibody

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBL4A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EGEAQRLADS PPPQVWQLIS KVLARHFSAA DASRVLEQLQ RDYERSLSRL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against UBL4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBL4A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 157 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBL4A

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Alternative Name: UBL4A (UBL4A Products)

Background: UBL4A is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. UBL4A is the TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Alias Symbols: DX254E, DXS254E, G6PD, GDX, UBL4, GET5, MDY2, TMA24
Protein Interaction Partner: MEOX2, HUWE1, TRAF4, CDCA7L, FAF1, VAPB, SGTA, SHFM1, UBC, CDK18, HIPK4, FAF2, UQCRC1, UBE2G2, UBA52, GET4, RAB14, PTPLAD1, CD320, HSD17B12, GEMIN4, UBQLN1, PABPC1, FAM162A, PRPF31, GEMIN5, METTL21B, RPL36, CORO1C, RPL13A, PHB2, DDX20, ERLIN2, RER1, RAB35
Protein Size: 157

Molecular Weight: 18 kDa

Gene ID: 8266

NCBI Accession: NM_014235, NP_055050

UniProt: B7NZQ9

Pathways: Ubiquitin Proteasome Pathway