UBL4A antibody (C-Term)

Catalog No. ABIN2788050

The Rabbit Polyclonal anti-UBL4A antibody is suitable to detect UBL4A in samples from Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse and Pig. It has been validated for WB.

Quick Overview for UBL4A antibody (C-Term) (ABIN2788050)

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBL4A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBL4A Antibody

Binding Specificity: C-Term

Sequence: SAADASRVLE QLQRDYERSL SRLTLDDIER LASRFLHPEV TETMEKGFSK

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against UBL4A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human UBL4A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 157 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UBL4A

Target: UBL4A (Ubiquitin-Like 4A (UBL4A))

Alternative Name: UBL4A

Background: UBL4A is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. UBL4A is the TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Alias Symbols: DX254E, DXS254E, G6PD, GDX, UBL4, GET5, MDY2, TMA24
Protein Interaction Partner: MEOX2, HUWE1, TRAF4, CDCA7L, FAF1, VAPB, SGTA, SHFM1, UBC, CDK18, HIPK4, FAF2, UQCRC1, UBE2G2, UBA52, GET4, RAB14, PTPLAD1, CD320, HSD17B12, GEMIN4, UBQLN1, PABPC1, FAM162A, PRPF31, GEMIN5, METTL21B, RPL36, CORO1C, RPL13A, PHB2, DDX20, ERLIN2, RER1, RAB35
Protein Size: 157

Molecular Weight: 18 kDa

Gene ID: 8266

NCBI Accession: NM_014235, NP_055050

UniProt: B7NZQ9

Pathways: Ubiquitin Proteasome Pathway