UBL4A antibody (C-Term)
Quick Overview for UBL4A antibody (C-Term) (ABIN2788050)
Target
See all UBL4A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- SAADASRVLE QLQRDYERSL SRLTLDDIER LASRFLHPEV TETMEKGFSK
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Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 79%, Rat: 86%
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Characteristics
- This is a rabbit polyclonal antibody against UBL4A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human UBL4A
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 157 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBL4A (Ubiquitin-Like 4A (UBL4A))
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Alternative Name
- UBL4A
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Background
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UBL4A is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. UBL4A is the TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Alias Symbols: DX254E, DXS254E, G6PD, GDX, UBL4, GET5, MDY2, TMA24
Protein Interaction Partner: MEOX2, HUWE1, TRAF4, CDCA7L, FAF1, VAPB, SGTA, SHFM1, UBC, CDK18, HIPK4, FAF2, UQCRC1, UBE2G2, UBA52, GET4, RAB14, PTPLAD1, CD320, HSD17B12, GEMIN4, UBQLN1, PABPC1, FAM162A, PRPF31, GEMIN5, METTL21B, RPL36, CORO1C, RPL13A, PHB2, DDX20, ERLIN2, RER1, RAB35
Protein Size: 157 -
Molecular Weight
- 18 kDa
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Gene ID
- 8266
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NCBI Accession
- NM_014235, NP_055050
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UniProt
- B7NZQ9
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Pathways
- Ubiquitin Proteasome Pathway
Target
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