UFD1L antibody (Middle Region)

Catalog No. ABIN2788062

The Rabbit Polyclonal anti-UFD1L antibody has been validated for WB. It is suitable to detect UFD1L in samples from Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow and Rabbit.

Quick Overview for UFD1L antibody (Middle Region) (ABIN2788062)

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio), Cow, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UFD1L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UFD1L Antibody

Binding Specificity: Middle Region

Sequence: NYNEKIYELR VMETKPDKAV SIIECDMNVD FDAPLGYKEP ERQVQHEEST

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against UFD1L. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UFD1L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 307 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Alternative Name: UFD1L

Background: The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Alias Symbols: UFD1
Protein Interaction Partner: HUWE1, YOD1, VCP, UBC, SHFM1, SUZ12, BTRC, EZH2, PDCD4, NPLOC4, NFKBIA, NUB1, NEDD8, CAV1, ADRB2, FAF1, TXLNA, UNC45A, VPS33B, UBE3A, UBE2N, PSMD7, SPRTN, UBXN6, GZMK, ERLIN2, ITPR1, PPHLN1, ANAPC2, TIAM2, TAF1C, TP53, SNX1, MASP1, PIK3CA, NGFR, IGHM, F13
Protein Size: 307

Molecular Weight: 34 kDa

Gene ID: 7353

NCBI Accession: NM_005659, NP_005650

UniProt: Q92890