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SYT1 antibody (N-Term)

This Rabbit Polyclonal antibody specifically detects SYT1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Rabbit, Dog, Horse and Guinea Pig.
Catalog No. ABIN2788073

Quick Overview for SYT1 antibody (N-Term) (ABIN2788073)

Target

See all SYT1 Antibodies
SYT1 (Synaptotagmin I (SYT1))

Reactivity

  • 87
  • 77
  • 54
  • 10
  • 7
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Rat, Mouse, Cow, Rabbit, Dog, Horse, Guinea Pig

Host

  • 92
  • 12
  • 8
  • 6
  • 2
  • 1
  • 1
Rabbit

Clonality

  • 102
  • 20
Polyclonal

Conjugate

  • 68
  • 8
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SYT1 antibody is un-conjugated

Application

  • 70
  • 44
  • 36
  • 16
  • 14
  • 13
  • 13
  • 10
  • 9
  • 8
  • 5
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 15
    • 14
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequence

    KDVKDLGKTM KDQALKDDDA ETGLTDGEEK EEPKEEEKLG KLQYSLDYDF

    Predicted Reactivity

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    Characteristics

    This is a rabbit polyclonal antibody against Syt1. It was validated on Western Blot.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Syt1
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 421 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    SYT1 (Synaptotagmin I (SYT1))

    Alternative Name

    Syt1

    Background

    Syt1 is a integral component of synaptic vesicle membranes, It is important for exocytosis and vesicle trafficking to the active zone of synapses and may be the calcium sensor for calcium-dependent exocytosis.
    Alias Symbols: P65
    Protein Interaction Partner: Ubc, Rims1, Stx1a, Cacna1c, Cacna1b, Syt1, Wnk1, Snap25, Stx1b, Stx3, Stx4, Nrxn1, Sv2a,
    Protein Size: 421

    Molecular Weight

    46 kDa

    Gene ID

    25716

    NCBI Accession

    NM_001033680, NP_001028852

    UniProt

    P21707

    Pathways

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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