SYT1 antibody

Catalog No. ABIN7075794

The Rabbit Polyclonal anti-SYT1 antibody is suitable to detect SYT1 in samples from Human, Rat and Mouse. It has been validated for WB, IHC and IF.

Quick Overview for SYT1 antibody (ABIN7075794)

Target: SYT1 (Synaptotagmin I (SYT1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SYT1 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse SYT1

Application Details

Application Notes: WB (M,R) 1:500-1:1000, IHC/IF (H) 1:1000-1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SYT1

Target: SYT1 (Synaptotagmin I (SYT1))

Alternative Name: SYT1

Background: This protein calcium sensor that participates in triggering neurotransmitter release at the synapse . May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.

Molecular Weight: 60 kDa

Gene ID: 20979

NCBI Accession: NP_001239270

UniProt: P46096

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport