Synaptotagmin V antibody (Middle Region)

Catalog No. ABIN2788086

This anti-Synaptotagmin V antibody is a Rabbit Polyclonal antibody detecting Synaptotagmin V in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig and Horse.

Quick Overview for Synaptotagmin V antibody (Middle Region) (ABIN2788086)

Target: Synaptotagmin V (SYT5)

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Synaptotagmin V antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Synaptotagmin V Antibody

Binding Specificity: Middle Region

Sequence: YLLPDKRRRY ETKVHRQTLN PHFGETFAFK VPYVELGGRV LVMAVYDFDR

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 93%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SYT5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SYT5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 386 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Synaptotagmin V

Target: Synaptotagmin V (SYT5)

Alternative Name: SYT5

Background: Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).
Alias Symbols: -
Protein Interaction Partner: POLR2E, NRXN1, SYT3, SYT5, RAB1A,
Protein Size: 386

Molecular Weight: 43 kDa

Gene ID: 6861

NCBI Accession: NM_003180, NP_003171

UniProt: O00445

Pathways: Synaptic Vesicle Exocytosis