ELMO1 antibody (C-Term)

Catalog No. ABIN2788147

This Rabbit Polyclonal antibody specifically detects ELMO1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for ELMO1 antibody (C-Term) (ABIN2788147)

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELMO1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ELMO1 Antibody

Binding Specificity: C-Term

Sequence: TQTPPGMLAL DNMLYFAKHH QDAYIRIVLE NSSREDKHEC PFGRSSIELT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ELMO1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ELMO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 727 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELMO1

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Alternative Name: ELMO1

Background: The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: CED-12, CED12, ELMO-1, KIAA0281, MGC126406
Protein Interaction Partner: ZNF398, TRIM54, UBC, PTGS2, DOCK1, BAG3, FGD1, RHOG, HCK, JMJD6, DOCK2,
Protein Size: 727

Molecular Weight: 84 kDa

Gene ID: 9844

NCBI Accession: NM_014800, NP_055615

UniProt: Q92556