PLEKHG2 antibody (Middle Region)
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- Target See all PLEKHG2 Antibodies
- PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Zebrafish (Danio rerio), Dog, Guinea Pig, Cow, Mouse, Rabbit, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PLEKHG2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DLTIPKHRHL LQAKNQEEKR LWIHCLQRLF FENHPASIPA KAKQVLLENS
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PLEKHG2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PLEKHG2
- Top Product
- Discover our top product PLEKHG2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1344 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))
- Alternative Name
- PLEKHG2 (PLEKHG2 Products)
- Synonyms
- ARHGEF42 antibody, CLG antibody, AI194308 antibody, Clg antibody, Cslg antibody, pleckstrin homology and RhoGEF domain containing G2 antibody, pleckstrin homology domain containing, family G (with RhoGef domain) member 2 antibody, PLEKHG2 antibody, Plekhg2 antibody
- Background
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PLEKHG2 may be a transforming oncogene with exchange activity for CDC42. PLEKHG2 may be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.PLEKHG2 activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
Alias Symbols: CLG, DKFZp667J2325, FLJ00018, FLJ22458, FLJ38638, ARHGEF42
Protein Interaction Partner: ACTN3, XRN1, APP, GNG2, GNB1, RAC1, RHOA, CDC42,
Protein Size: 1344 - Molecular Weight
- 144 kDa
- Gene ID
- 64857
- NCBI Accession
- NM_022835, NP_073746
- UniProt
- Q9H7P9
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