PLEKHG2 antibody (Middle Region)

Catalog No. ABIN2788148

The Rabbit Polyclonal anti-PLEKHG2 antibody is suitable to detect PLEKHG2 in samples from Human, Dog, Guinea Pig, Zebrafish (Danio rerio), Cow, Mouse, Rabbit and Rat. It has been validated for WB.

Quick Overview for PLEKHG2 antibody (Middle Region) (ABIN2788148)

Target: PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))

Reactivity: Human, Dog, Guinea Pig, Zebrafish (Danio rerio), Cow, Mouse, Rabbit, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEKHG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PLEKHG2 Antibody

Binding Specificity: Middle Region

Sequence: DLTIPKHRHL LQAKNQEEKR LWIHCLQRLF FENHPASIPA KAKQVLLENS

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PLEKHG2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLEKHG2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1344 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLEKHG2

Target: PLEKHG2 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 2 (PLEKHG2))

Alternative Name: PLEKHG2

Background: PLEKHG2 may be a transforming oncogene with exchange activity for CDC42. PLEKHG2 may be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42.PLEKHG2 activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
Alias Symbols: CLG, DKFZp667J2325, FLJ00018, FLJ22458, FLJ38638, ARHGEF42
Protein Interaction Partner: ACTN3, XRN1, APP, GNG2, GNB1, RAC1, RHOA, CDC42,
Protein Size: 1344

Molecular Weight: 144 kDa

Gene ID: 64857

NCBI Accession: NM_022835, NP_073746

UniProt: Q9H7P9