ARHGEF2 antibody (C-Term)

Catalog No. ABIN2788156

This Rabbit Polyclonal antibody specifically detects ARHGEF2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Rabbit and Horse.

Quick Overview for ARHGEF2 antibody (C-Term) (ABIN2788156)

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARHGEF2 Antibody

Binding Specificity: C-Term

Sequence: NTSPGVTANG EARTFNGSIE LCRADSDSSQ RDRNGNQLRS PQEEALQRLV

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ARHGEF2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 986 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARHGEF2

Target: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Alternative Name: ARHGEF2

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp547L106, DKFZp547P1516, FLJ45440, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40
Protein Interaction Partner: RPP25L, UBC, CEP250, RPA3, RPA2, RPA1, PPP6C, FBXO6, ANKRD28, PPP6R1, YWHAB, MMS19, PEX14, VCP, NOTCH1, YWHAZ, MARK2, RHOA, AKT1, USP21, ELAVL1, SUMO1, MARK4, YWHAH, YWHAG, MYC, MAPK1, TAF10, CGN, YWHAE, PAK1, RAC1, RRAS2, PLCG1, WASF1, YWHAQ,
Protein Size: 986

Molecular Weight: 111 kDa

Gene ID: 9181

NCBI Accession: NM_001162383, NP_001155855

UniProt: Q92974

Pathways: Negative Regulation of intrinsic apoptotic Signaling