GUCA1B antibody (N-Term)

Catalog No. ABIN2788203

The Rabbit Polyclonal anti-GUCA1B antibody (ABIN2788203) specifically detects GUCA1B in WB. The antibody is reactive with Human, Mouse, Cow, Dog, Rabbit, Rat, Guinea Pig and Horse samples.

Quick Overview for GUCA1B antibody (N-Term) (ABIN2788203)

Target: GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))

Reactivity: Human, Mouse, Cow, Dog, Rabbit, Rat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCA1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GUCA1B Antibody

Binding Specificity: N-Term

Sequence: SGTLFMHEFK RFFKVTDDEE ASQYVEGMFR AFDKNGDNTI DFLEYVAALN

Predicted Reactivity: Cow: 79%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against GUCA1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GUCA1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 200 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GUCA1B

Target: GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))

Alternative Name: GUCA1B

Background: The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa.
Alias Symbols: DKFZp686E1183, GCAP2, GUCA2, RP48
Protein Interaction Partner: GUCY2D, GUCY2F,
Protein Size: 200

Molecular Weight: 23 kDa

Gene ID: 2979

NCBI Accession: NM_002098, NP_002089

UniProt: Q9UMX6

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction