Fascin 2 antibody (Middle Region)

Catalog No. ABIN2788215

The Rabbit Polyclonal anti-Fascin 2 antibody has been validated for WB. It is suitable to detect Fascin 2 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Cow and Horse.

Quick Overview for Fascin 2 antibody (Middle Region) (ABIN2788215)

Target: Fascin 2 (FSCN2)

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fascin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Fascin 2 Antibody

Binding Specificity: Middle Region

Sequence: AGTLKAGRNT RPGKDELFDL EESHPQVVLV AANHRYVSVR QGVNVSANQD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FSCN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FSCN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 516 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Fascin 2

Target: Fascin 2 (FSCN2)

Alternative Name: FSCN2

Background: This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RFSN, RP30
Protein Size: 516

Molecular Weight: 57 kDa

Gene ID: 25794

NCBI Accession: NM_001077182, NP_001070650

UniProt: O14926