Adenosine A2b Receptor antibody (C-Term)

Catalog No. ABIN2788277

Product Details anti-Adenosine A2b Receptor Antibody

Target: Adenosine A2b Receptor (ADORA2B)

Binding Specificity: C-Term

Reactivity: Human, Guinea Pig, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adenosine A2b Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AKSLAMIVGI FALCWLPVHA VNCVTLFQPA QGKNKPKWAM NMAILLSHAN

Predicted Reactivity: Dog: 79%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against ADORA2B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA2B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 332 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adenosine A2b Receptor

Target: Adenosine A2b Receptor (ADORA2B)

Alternative Name: ADORA2B (ADORA2B Products)

Background: This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
Alias Symbols: ADORA2
Protein Interaction Partner: UBC, ZNF267, TPD52L2, SLC9A3R2, NTN1, EZR, DCC, ADA,
Protein Size: 332

Molecular Weight: 36 kDa

Gene ID: 136

NCBI Accession: NM_000676, NP_000667

UniProt: P29275

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process