ETFDH antibody (C-Term)
Quick Overview for ETFDH antibody (C-Term) (ABIN2788312)
Target
See all ETFDH AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- KTIGLHVTEY EDNLKNSWVW KELYSVRNIR PSCHGVLGVY GGMIYTGIFY
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Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against ETFDH. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ETFDH
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 617 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ETFDH (Electron-Transferring-Flavoprotein Dehydrogenase (ETFDH))
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Alternative Name
- ETFDH
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Background
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Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67- kDa precursor which is targeted to mitochondria and processed in a single step to a 64- kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia
Alias Symbols: ETFQO, MADD
Protein Interaction Partner: UBC, SUMO1,
Protein Size: 617 -
Molecular Weight
- 65 kDa
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Gene ID
- 2110
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NCBI Accession
- NM_004453, NP_004444
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UniProt
- Q16134
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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