CEACAM3 antibody (C-Term)

Catalog No. ABIN2788339

This Rabbit Polyclonal antibody specifically detects CEACAM3 in WB. It exhibits reactivity toward Human.

Quick Overview for CEACAM3 antibody (C-Term) (ABIN2788339)

Target: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CEACAM3 Antibody

Binding Specificity: C-Term

Sequence: AKTGRTSIQR DLKEQQPQAL APGRGPSHSS AFSMSPLSTA QAPLPNPRTA

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CEACAM3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CEACAM3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 252 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CEACAM3

Target: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Alternative Name: CEACAM3

Background: This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Alias Symbols: CD66D, CEA, CGM1, MGC119875, W264, W282
Protein Interaction Partner: CSNK1A1L, SRC, S100A8, CEACAM1,
Protein Size: 252

Molecular Weight: 23 kDa

Gene ID: 1084

NCBI Accession: NM_001815, NP_001806

UniProt: P40198