DOK4 antibody (C-Term)

Catalog No. ABIN2788378

This anti-DOK4 antibody is a Rabbit Polyclonal antibody detecting DOK4 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Pig.

Quick Overview for DOK4 antibody (C-Term) (ABIN2788378)

Target: DOK4 (Docking Protein 4 (DOK4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DOK4 Antibody

Binding Specificity: C-Term

Sequence: GSQNIAEASS YAGEGYGAAQ ASSETDLLNR FILLKPKPSQ GDSSEAKTPS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 77%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DOK4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DOK4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DOK4

Target: DOK4 (Docking Protein 4 (DOK4))

Alternative Name: DOK4

Background: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway
Alias Symbols: FLJ10488
Protein Interaction Partner: BAG3, ERBB2, EGFR, ELAVL1, TEK, SRC, CRK, RET, INSR, IGF1R, RASA1, FYN,
Protein Size: 326

Molecular Weight: 36 kDa

Gene ID: 55715

NCBI Accession: NM_018110, NP_060580

UniProt: Q8TEW6