LOXL3 antibody (Middle Region)

Catalog No. ABIN2788388

The Rabbit Polyclonal anti-LOXL3 antibody has been validated for WB. It is suitable to detect LOXL3 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit.

Quick Overview for LOXL3 antibody (Middle Region) (ABIN2788388)

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LOXL3 Antibody

Binding Specificity: Middle Region

Sequence: AASSGQKKQQ QSKPQGEARV RLKGGAHPGE GRVEVLKAST WGTVCDRKWD

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against LOXL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LOXL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 753 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LOXL3

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Alternative Name: LOXL3

Background: LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Alias Symbols: LOXL
Protein Interaction Partner: APMAP,
Protein Size: 753

Molecular Weight: 80 kDa

Gene ID: 84695

NCBI Accession: NM_032603, NP_115992

UniProt: P58215