LOXL3 antibody (C-Term)

Catalog No. ABIN953203

This Rabbit Polyclonal antibody specifically detects LOXL3 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for LOXL3 antibody (C-Term) (ABIN953203)

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-LOXL3 Antibody

Binding Specificity: AA 722-752, C-Term

Specificity: This antibody recognizes Human LOXL3 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 722-752 amino acids from the C-terminal region of human LOXL3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LOXL3

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Alternative Name: LOXL3

Background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.Synonyms: LOXL, Lysyl oxidase homolog 3, Lysyl oxidase-like protein 3

Molecular Weight: 83166 Da

Gene ID: 84695

NCBI Accession: NP_115992