Lp(a) antibody (N-Term)

Catalog No. ABIN2788390

This Rabbit Polyclonal antibody specifically detects Lp(a) in WB. It exhibits reactivity toward Human.

Quick Overview for Lp(a) antibody (N-Term) (ABIN2788390)

Target: Lp(a) (Lipoprotein (Lp(a)))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lp(a) antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Lp(a) Antibody

Binding Specificity: N-Term

Sequence: VPDPSTEASS EEAPTEQSPG VQDCYHGDGQ SYRGSFSTTV TGRTCQSWSS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against LPA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LPA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1169 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lp(a)

Target: Lp(a) (Lipoprotein (Lp(a)))

Alternative Name: LPA

Background: LPA is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the protein contains 2-43 copies of kringle-type domains.
Alias Symbols: LP, AK38, APOA, LPA
Protein Interaction Partner: CANX, FBLN5, MMP12, LRP2, APOH, FN1, FGB, ELANE, CELA1,
Protein Size: 1169

Molecular Weight: 120 kDa

Gene ID: 4018

NCBI Accession: NM_005577

UniProt: P08519