Lipoprotein Lipase antibody (C-Term)

Catalog No. ABIN2788391

The Rabbit Polyclonal anti-Lipoprotein Lipase antibody has been validated for WB and IHC. It is suitable to detect Lipoprotein Lipase in samples from Human, Rat, Cow, Pig, Goat, Horse, Dog, Rabbit and Sheep.

Quick Overview for Lipoprotein Lipase antibody (C-Term) (ABIN2788391)

Target: Lipoprotein Lipase (LPL)

Reactivity: Human, Rat, Cow, Pig, Goat, Horse, Dog, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipoprotein Lipase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Lipoprotein Lipase Antibody

Binding Specificity: C-Term

Sequence: LGYEINKVRA KRSSKMYLKT RSQMPYKVFH YQVKIHFSGT ESETHTNQAF

Predicted Reactivity: Cow: 86%, Dog: 79%, Goat: 86%, Horse: 86%, Human: 100%, Pig: 92%, Rabbit: 86%, Rat: 86%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against LPL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LPL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 475 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Lipoprotein Lipase

Target: Lipoprotein Lipase (LPL)

Alternative Name: LPL

Background: LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
Alias Symbols: HDLCQ11, LIPD
Protein Interaction Partner: LMF1, LPL, CALR, CCND1, APP, CUL3, UBC, PLK1, LUC7L2, KIAA1377, COPS6, ASCC2, RPL18A, UBE2Z, APOC2, LRP2, VLDLR, PTPN4, CETP, LRP1, EMD,
Protein Size: 475

Molecular Weight: 50 kDa

Gene ID: 4023

NCBI Accession: NM_000237, NP_000228

UniProt: P06858

Pathways: Lipid Metabolism