MAP4 antibody (N-Term)

Catalog No. ABIN2788397

This anti-MAP4 antibody is a Rabbit Polyclonal antibody detecting MAP4 in WB and IHC. Suitable for Human.

Quick Overview for MAP4 antibody (N-Term) (ABIN2788397)

Target: MAP4 (Microtubule-Associated Protein 4 (MAP4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAP4 Antibody

Binding Specificity: N-Term

Sequence: LKETERASPI KMDLAPSKDM GPPKENKKET ERASPIKMDL APSKDMGPPK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against MAP4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1152 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MAP4

Target: MAP4 (Microtubule-Associated Protein 4 (MAP4))

Alternative Name: MAP4

Background: MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.
Alias Symbols: DKFZp779A1753, MGC8617
Protein Interaction Partner: UBC, LGR4, RPA3, RPA2, RPA1, LSM8, WDHD1, HNRNPR, PDCD6, PPP4R1, MTA2, POLR2C, POLR2A, IARS, HNRNPF, EIF2S1, CSTF2, COG7, TARDBP, BAG3, ERBB2IP, SNTA1, LDLR, IL7R, FN1, TRAF3IP1, RPS20, GRK5, EPS15, AP2M1, USP21, CUL4A, POT1, ISG15, TERF1, SIRT7, SH3KBP1,
Protein Size: 1152

Molecular Weight: 121 kDa

Gene ID: 4134

NCBI Accession: NM_002375, NP_002366

UniProt: P27816

Pathways: p53 Signaling, Microtubule Dynamics