ST5 antibody (Middle Region)

Catalog No. ABIN2788427

The Rabbit Polyclonal anti-ST5 antibody has been validated for WB and IHC. It is suitable to detect ST5 in samples from Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit and Dog.

Quick Overview for ST5 antibody (Middle Region) (ABIN2788427)

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ST5 Antibody

Binding Specificity: Middle Region

Sequence: VPKPKRTFEY EADKNPKSKP SNGLPPSPTP AAPPPLPSTP APPVTRRPKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ST5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ST5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1137 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Alternative Name: ST5

Background: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Alias Symbols: DENND2B, HTS1, MGC33090, p126
Protein Interaction Partner: SMAD2, UBC, ABL1, SFN,
Protein Size: 1137

Molecular Weight: 126 kDa

Gene ID: 6764

NCBI Accession: NM_005418, NP_005409

UniProt: P78524