DTNBP1 antibody (C-Term)

Catalog No. ABIN2788443

This anti-DTNBP1 antibody is a Rabbit Polyclonal antibody detecting DTNBP1 in WB. Suitable for Human and Cow.

Quick Overview for DTNBP1 antibody (C-Term) (ABIN2788443)

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DTNBP1 Antibody

Binding Specificity: C-Term

Sequence: PESSTCQNEI TLQVPNPSEL RAKPPSSSST CTDSATRDIS EGGESPVVQS

Predicted Reactivity: Cow: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against DTNBP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DTNBP1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DTNBP1

Target: DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))

Alternative Name: DTNBP1

Background: This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Protein Interaction Partner: SSC5D, KANSL1, P4HA3, CCDC153, TXLNB, HAUS1, IFT20, ELOVL7, CCDC146, BRK1, C19orf66, CCHCR1, CCDC53, TRIM27, KIFC3, DTNB, SDCBP, NDN, UBC, TRIM32, KALRN, RAB11A, IPO5, BRF1, DCTN1, CCNA2, DST, SFR1, TRIM9, NUF2, RBSN, EXOC4, ZNF490, SYBU, NBEA, TRAF3IP1,
Protein Size: 270

Molecular Weight: 29 kDa

Gene ID: 84062

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling