CD63 antibody (C-Term)

Catalog No. ABIN786262

This Rabbit Polyclonal antibody specifically detects CD63 in WB. It exhibits reactivity toward Human.

Quick Overview for CD63 antibody (C-Term) (ABIN786262)

Target: CD63

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD63 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD63 Antibody

Binding Specificity: C-Term

Sequence: TDWEKIPSMS KNRVPDSCCI NVTVGCGINF NEKAIHKEGC VEKIGGWLRK

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CD63. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 238 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CD63

Target: CD63

Alternative Name: CD63

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.
Alias Symbols: LAMP-3, ME491, MLA1, OMA81H, TSPAN30
Protein Interaction Partner: UBC, VKORC1, ATP6V1B1, env, RNF13, gag, CD81, PI4K2A, CD82, AP4M1, PTGFRN, TIMP1, ITGA6, CD9, HLA-DRA, HLA-DMB, SRF, ITGB1, HLA-DOB, KIT,
Protein Size: 238

Molecular Weight: 26 kDa

Gene ID: 967

NCBI Accession: NM_001780, NP_001771

UniProt: P08962