PIGC antibody (C-Term)

Catalog No. ABIN2788604

The Rabbit Polyclonal anti-PIGC antibody has been validated for WB. It is suitable to detect PIGC in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse and Zebrafish (Danio rerio).

Quick Overview for PIGC antibody (C-Term) (ABIN2788604)

Target: PIGC (Phosphatidylinositol Glycan C (PIGC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIGC Antibody

Binding Specificity: C-Term

Sequence: AVGAVLFALL LMSISCLCPF YLIRLQLFKE NIHGPWDEAE IKEDLSRFLS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PIGC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PIGC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 297 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIGC

Target: PIGC (Phosphatidylinositol Glycan C (PIGC))

Alternative Name: PIGC

Background: This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum.
Alias Symbols: GPI2, MGC2049
Protein Interaction Partner: KLF10, DPM2, ZHX1, PIGQ,
Protein Size: 297

Molecular Weight: 33 kDa

Gene ID: 5279

NCBI Accession: NM_002642, NP_002633

UniProt: Q92535

Pathways: Inositol Metabolic Process