Myeloperoxidase antibody (N-Term)

Catalog No. ABIN2788634

This anti-Myeloperoxidase antibody is a Rabbit Polyclonal antibody detecting Myeloperoxidase in WB. Suitable for Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Goat and Guinea Pig.

Quick Overview for Myeloperoxidase antibody (N-Term) (ABIN2788634)

Target: Myeloperoxidase (MPO)

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Goat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myeloperoxidase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Myeloperoxidase Antibody

Binding Specificity: N-Term

Sequence: QLNVLSKSSG CAYQDVGVTC PEQDKYRTIT GMCNNRRSPT LGASNRAFVR

Predicted Reactivity: Cow: 79%, Dog: 83%, Goat: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MPO. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MPO

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 745 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Myeloperoxidase

Target: Myeloperoxidase (MPO)

Alternative Name: MPO

Background: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.
Alias Symbols: -
Protein Interaction Partner: RAD21, Dynll1, MPO, CP,
Protein Size: 745

Molecular Weight: 84 kDa

Gene ID: 4353

NCBI Accession: NM_000250, NP_000241

UniProt: P05164

Pathways: Chromatin Binding