Superoxide dismutase copper chaperone antibody (Middle Region)

Catalog No. ABIN2788651

This Rabbit Polyclonal antibody specifically detects Superoxide dismutase copper chaperone in WB. It exhibits reactivity toward Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Horse, Guinea Pig, Sheep and Zebrafish (Danio rerio).

Quick Overview for Superoxide dismutase copper chaperone antibody (Middle Region) (ABIN2788651)

Target: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Horse, Guinea Pig, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Superoxide dismutase copper chaperone antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Superoxide dismutase copper chaperone Antibody

Binding Specificity: Middle Region

Sequence: LHGLHVHQYG DLTNNCNSCG NHFNPDGASH GGPQDSDRHR GDLGNVRADA

Predicted Reactivity: Cow: 92%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 92%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against CCS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 274 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Superoxide dismutase copper chaperone

Target: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Alternative Name: CCS

Background: Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Alias Symbols: MGC138260
Protein Interaction Partner: SLC31A1, SOD1, UBC, XIAP, YWHAG, CCS, APBA1,
Protein Size: 274

Molecular Weight: 29 kDa

Gene ID: 9973

NCBI Accession: NM_005125, NP_005116

UniProt: O14618

Pathways: Transition Metal Ion Homeostasis