FMO2 antibody (N-Term)
Quick Overview for FMO2 antibody (N-Term) (ABIN2788732)
Target
See all FMO2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- KYIQFQTTVL SVRKCPDFSS SGQWKVVTQS NGKEQSAVFD AVMVCSGHHI
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Predicted Reactivity
- Cow: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against FMO2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human FMO2
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 471 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))
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Alternative Name
- FMO2
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Background
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The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Alias Symbols: FLJ40826, FMO1B1
Protein Size: 471 -
Molecular Weight
- 54 kDa
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Gene ID
- 2327
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NCBI Accession
- NM_001460, NP_001451
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UniProt
- Q99518
Target
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