FMO2 antibody (N-Term)

Catalog No. ABIN2788732

The Rabbit Polyclonal anti-FMO2 antibody is suitable to detect FMO2 in samples from Human, Rat, Mouse, Cow, Horse, Rabbit and Guinea Pig. It has been validated for WB.

Quick Overview for FMO2 antibody (N-Term) (ABIN2788732)

Target: FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

Reactivity: Human, Rat, Mouse, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMO2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FMO2 Antibody

Binding Specificity: N-Term

Sequence: KYIQFQTTVL SVRKCPDFSS SGQWKVVTQS NGKEQSAVFD AVMVCSGHHI

Predicted Reactivity: Cow: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FMO2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMO2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FMO2

Target: FMO2 (Flavin Containing Monooxygenase 2 (Non-Functional) (FMO2))

Alternative Name: FMO2

Background: The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1.
Alias Symbols: FLJ40826, FMO1B1
Protein Size: 471

Molecular Weight: 54 kDa

Gene ID: 2327

NCBI Accession: NM_001460, NP_001451

UniProt: Q99518