2B4 antibody (C-Term)

Catalog No. ABIN2788782

The Rabbit Polyclonal anti-2B4 antibody is suitable to detect 2B4 in samples from Human. It has been validated for WB.

Quick Overview for 2B4 antibody (C-Term) (ABIN2788782)

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 2B4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-2B4 Antibody

Binding Specificity: C-Term

Sequence: FRFWPFLVII VILSALFLGT LACFCVWRRK RKEKQSETSP KEFLTIYEDV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CD244. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 365 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for 2B4

Target: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Alternative Name: CD244

Background: This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: 2B4, NAIL, NKR2B4, Nmrk, SLAMF4
Protein Interaction Partner: SH2D1A, FYN, SH2D1B, ARHGEF7, LAT, CD247, CD48,
Protein Size: 365

Molecular Weight: 40 kDa

Gene ID: 51744

NCBI Accession: NM_016382, NP_057466

UniProt: B2R820