DTNA antibody (C-Term)

Catalog No. ABIN2788807

This anti-DTNA antibody is a Rabbit Polyclonal antibody detecting DTNA in WB. Suitable for Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Saccharomyces cerevisiae.

Quick Overview for DTNA antibody (C-Term) (ABIN2788807)

Target: DTNA (Dystrobrevin alpha (DTNA))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTNA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DTNA Antibody

Binding Specificity: C-Term

Sequence: GATTSTMRGD MVTEDADPYV QPEDENYEND SVRQLENELQ MEEYLKQKLQ

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 92%, Yeast: 83%

Characteristics: This is a rabbit polyclonal antibody against DTNA. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 452 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DTNA

Target: DTNA (Dystrobrevin alpha (DTNA))

Alternative Name: DTNA

Background: The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: D18S892E, DRP3, DTN, FLJ96209, LVNC1
Protein Interaction Partner: SNTA1, ADRA1D, TJP1, ACTB, MLC1, NUP62, SEC23A, SEC24C, PSEN1, MYO1E, GFI1B, MARK2, SYNC, SNTG2, SNTG1, KCNJ12, SYNM, DTNBP1, SNTB2, SNTB1, DMD, DRP2, UTRN, ACTA1,
Protein Size: 452

Molecular Weight: 49 kDa

Gene ID: 1837

NCBI Accession: NM_001198942, NP_001185871

UniProt: B4DIR0