ROCK2 antibody (Middle Region)

Catalog No. ABIN2788813

This anti-ROCK2 antibody is a Rabbit Polyclonal antibody detecting ROCK2 in WB and IHC. Suitable for Human, Rat, Mouse, Cow, Pig, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for ROCK2 antibody (Middle Region) (ABIN2788813)

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reactivity: Human, Rat, Mouse, Cow, Pig, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ROCK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ROCK2 Antibody

Binding Specificity: Middle Region

Sequence: KNAEYQRKAD HEADKKRNLE NDVNSLKDQL EDLKKRNQNS QISTEKVNQL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against ROCK2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ROCK2

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Alternative Name: ROCK2

Background: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Alias Symbols: KIAA0619, ROCK-II
Protein Interaction Partner: UBC, FAM21A, RABGEF1, GPHN, KIAA0196, MTA2, ZW10, NHP2L1, LMNA, MAGEC1, ELAVL1, PPP1R12A, STAU1, RHOA, IKBKE, STK16, MBP,
Protein Size: 1388

Molecular Weight: 153 kDa

Gene ID: 9475

NCBI Accession: NM_004850, NP_004841

UniProt: O75116

Pathways: Microtubule Dynamics, WNT Signaling, Tube Formation