Melatonin Receptor 1A antibody (C-Term)

Catalog No. ABIN2788825

The Rabbit Polyclonal anti-Melatonin Receptor 1A antibody has been validated for WB. It is suitable to detect Melatonin Receptor 1A in samples from Human, Cow, Goat, Sheep, Dog, Guinea Pig, Horse and Rabbit.

Quick Overview for Melatonin Receptor 1A antibody (C-Term) (ABIN2788825)

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human, Cow, Goat, Sheep, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Melatonin Receptor 1A Antibody

Binding Specificity: C-Term

Sequence: GLLNQNFRKE YRRIIVSLCT ARVFFVDSSN DVADRVKWKP SPLMTNNNVV

Predicted Reactivity: Cow: 79%, Dog: 91%, Goat: 79%, Guinea Pig: 82%, Horse: 83%, Human: 100%, Rabbit: 83%, Sheep: 79%

Characteristics: This is a rabbit polyclonal antibody against MTNR1A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 350 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: MTNR1A

Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Alias Symbols: MEL-1A-R, MT1
Protein Interaction Partner: VAPB, IRS4, RAP1A, RAC1, HSPA5, GNB1, GNAI3, GNAI2, GNAI1, GNB4, LRRC59, TMEM33, HNRNPA0, RAB10, PGRMC1, PDIA6, FLNA, EEF1G, CNP, CANX, CALR, GPR50, GNA13, DPM1, MTNR1B, MTNR1A, GNA11,
Protein Size: 350

Molecular Weight: 39 kDa

Gene ID: 4543

NCBI Accession: NM_005958, NP_005949

UniProt: P48039